Use of DNA probes from the 5′ flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus
作者： Karyn Steere , Beth Sidwell , Robin Leach , Francis E. Ward , Joel D. Taurog
DOI: 10.1016/0198-8859(86)90042-X
关键词: DNA sequencing 、 Biology 、 5' flanking region 、 HLA-B locus 、 Genetics 、 HLA-B gene 、 Gene 、 Hybridization probe 、 Homology (biology) 、 Molecular biology 、 Allele 、 Immunology 、 Immunology and Allergy 、 General Medicine
摘要: Abstract Two DNA probes isolated from the region 5′ to HLA-B gene are described. One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles HLA-B. Both used show high level sequence homology between flanking and HLA-C.
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