Effect of Reduced Oxygen Tension Upon Formed Elements of Blood of Hypophysectomized Animals.

摘要: It has been suggested1, 2 that the hypophysis, in addition to its many other functions, may play a part erythropoiesis.It long known man and animal, under conditions of reduced oxygen tension, there occurs an increase hemoglobin, erythrocytes reticulocytes blood, hyperplasia bone marrow. was thought if hypophysis furnished hormone which affected erythrogenetic tissues, response diminution tension tissues hypophysectomized animals might be deficient one or more respects. To test this hypothesis, 8 male white rats weighing 150 220 gm. were after complete blood counts done by usual methods. Erythrocyte duplicate; reticulocyte 1,000 cells on cover slip smear stained with cresyl blue, hemoglobin determinations Haden-Hauser hemoglobinometer. Eight days later, 4 experimental normal controls similar weight placed ...