Increased Erythropoiesis Induced by Androgenic-Hormone Therapy

作者: B. J. Kennedy , A. Sigrid Gilbertsen

DOI: 10.1056/NEJM195704182561601

关键词: ErythropoiesisMedicineInternal medicineHemoglobinHormone therapyHormoneEndocrinologyHyperplasiaBone marrowCancerHematocritGeneral Medicine

摘要: THE administration of androgenic hormones to women with advanced breast cancer has been associated an unusual alteration in erythropoietic activity.1 2 3 4 5 6 7 8 9 10 This consisted increases hemoglobin, red-cell count and hematocrit, hyperplasia the erythroid elements bone marrow. The increase activity is accompanied by clinical symptoms signs characteristic polycythemia. observations suggest that are a specific stimulating factor erythropoiesis and, when administered massive doses over prolonged period, will polycythemic level.10 Investigators hormone therapy have aware . . .

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