DOES QUININE IN THE INDUCTION OF LABOR HAVE A DELETERIOUS EFFECT ON THE FETUS

摘要: Quinine for many years has been credited with oxytocic properties, but there appears to be some difference of opinion as regards its efficiency when so employed. Sollmann1states that "moderate doses quinine stimulate, and high depress, the contractions tone uterus, excised in situ. The stimulant action increases excitability uterus process pregnancy. Clinically, little or no effects unless pains have started. It is therefore ineffective inducing premature labor." He further states it used clinically stimulate weak labor adds often difficult prove clinical response after oral administration because slow absorption. Dodek,2working same institution under Sollmann's guidance employing a new recording apparatus, found drug had effect administered two pregnant women at term