The relationship of blood velocity as measured by transcranial doppler ultrasonography to cerebral blood flow as determined by stable xenon computed tomographic studies after aneurysmal subarachnoid hemorrhage.

摘要: Transcranial doppler (TCD) ultrasonography is often used to guide the management of patients with subarachnoid hemorrhage (SAH). However, correlation between increased blood velocity as measured by TCD and angiographic vasospasm was established before routine use hypervolemia/hemodilution administration nimodipine did not address flow. The relationship local cerebral flow (LCBF) in SAH managed these modalities unknown. Patients presenting aneurysmal January 1992 September 1993 who underwent xenon computed tomographic (Xe/CT) LCBF studies within 12 hours were retrospectively studied. Fifty a total 94 paired studies, encompassing 709 vascular territories. All treated hypervolemia/hemodilution. Hematocrit, pressure, partial carbon dioxide pressure similar at time Xe/CT measurement LCBF. When middle artery (MCA) 31 ml/100 g/min had 169 cm/s (P = 0.006). High associated high all territories, reaching significance but internal carotid artery. At each study, 41 neurological examinations focal 53 nonfocal. MCA contralateral deficit significantly less than territories without corresponding clinical deficits 0.01), whereas peak systolic velocities different 0.71). Territories increases > 50 cm/s/24 h have statistically 0.183). Our results suggest that revealed correlates ischemia. No difference found rapid MCA. Furthermore, although corresponded decreased MCA, correlate findings. Therapeutic decisions based solely on might be inappropriate potentially harmful. are useful guiding SAH.