Management of hemolytic uremic syndrome.

作者: Chantal Loirat , Jeffrey Saland , Martin Bitzan

DOI: 10.1016/J.LPM.2011.11.013

关键词: Atypical hemolytic uremic syndromeDiseaseTherapeutic approachPlasmapheresisMedicineShiga toxin producingPopulationEculizumabPediatricsKidney transplantation

摘要: 2011 has been a special year for hemolytic uremic syndrome (HUS): on the one hand, dramatic epidemic of Shiga toxin producing E. coli -associated HUS in Germany brought disease to attention general population, other hand it when eculizumab, first complement blocker available clinical practice, was demonstrated as potential new standard care atypical HUS. Here we review therapeutic options presently various forms and show how recent knowledge changed approach prognosis

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