Thrombotic Microangiopathy
作者： C. John Sperati , Alison R. Moliterno
DOI: 10.1016/J.HOC.2015.02.002
关键词:
摘要: Thrombotic microangiopathies (TMA) such as atypical hemolytic uremic syndrome (aHUS) have evolved from rare, fulminant childhood afflictions to uncommon diseases with acute and chronic phases involving both children adults. Breakthroughs in complement coagulation regulation allowed redefinition of specific entities despite substantial phenotypic mimicry. Reconciliation phenotypes delivery life saving therapies require a multidisciplinary team experts. The purpose this review is describe advances the molecular pathophysiology aHUS share 2014 experience Johns Hopkins TMA Registry applying diagnostic assays, reporting disease associations, genetic testing.
elsevier.com
sci-hub.se 参考文章(104)
Sacks Sh, Martin J, Zhou W, Pani A, Campbell Rd, Complement C3 gene expression and regulation in human glomerular epithelial cells. Immunology. ,vol. 79, pp. 348- 354 ,(1993)
J CAMERON, PLASMA-C3 IN HqMOLYTIC-URqMIC SYNDROME AND THROMBOTIC THROMBOCYTOPENIC PURPURA The Lancet. ,vol. 302, pp. 975- ,(1973) , 10.1016/S0140-6736(73)92645-7
Erik Zimmermann-Nielsen, Henning Grønbæk, Jens Frederik Dahlerup, Gunnar Baatrup, Ole Thorlacius-Ussing, Complement activation capacity in plasma before and during high-dose prednisolone treatment and tapering in exacerbations of Crohn's disease and ulcerative colitis. BMC Gastroenterology. ,vol. 5, pp. 31- 31 ,(2005) , 10.1186/1471-230X-5-31
Maren Sullivan, Zoran Erlic, Michael M. Hoffmann, Klaus Arbeiter, Ludwig Patzer, Klemens Budde, Bernd Hoppe, Martin Zeier, Karl Lhotta, Lisa A. Rybicki, Andreas Bock, Gani Berisha, Hartmut PH Neumann, Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome Annals of Human Genetics. ,vol. 74, pp. 17- 26 ,(2010) , 10.1111/J.1469-1809.2009.00554.X
J. Zuber, M. Le Quintrec, S. Krid, C. Bertoye, V. Gueutin, A. Lahoche, N. Heyne, G. Ardissino, V. Chatelet, L.-H. Noël, M. Hourmant, P. Niaudet, V. Frémeaux-Bacchi, E. Rondeau, C. Legendre, C. Loirat, , Eculizumab for Atypical Hemolytic Uremic Syndrome Recurrence in Renal Transplantation American Journal of Transplantation. ,vol. 12, pp. 3337- 3354 ,(2012) , 10.1111/J.1600-6143.2012.04252.X
John P. Atkinson, Michael M. Frank, Effect of Cortisone Therapy on Serum Complement Components Journal of Immunology. ,vol. 111, pp. 1061- 1066 ,(1973)
Owen A. Hawksworth, Liam G. Coulthard, Stephen M. Taylor, Ernst J. Wolvetang, Trent M. Woodruff, Brief Report: Complement C5a Promotes Human Embryonic Stem Cell Pluripotency in the Absence of FGF2 Stem Cells. ,vol. 32, pp. 3278- 3284 ,(2014) , 10.1002/STEM.1801
Konstantinos Ritis, Michael Doumas, Dimitrios Mastellos, Anastasia Micheli, Stavros Giaglis, Paola Magotti, Stavros Rafail, Georgios Kartalis, Paschalis Sideras, John D. Lambris, A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. Journal of Immunology. ,vol. 177, pp. 4794- 4802 ,(2006) , 10.4049/JIMMUNOL.177.7.4794
C. M. Taylor, C. Chua, A. J. Howie, R. A. Risdon, Clinico-pathological findings in diarrhoea-negative haemolytic uraemic syndrome. Pediatric Nephrology. ,vol. 19, pp. 419- 425 ,(2004) , 10.1007/S00467-003-1385-9
Michael K. Pangburn, Hans J. Müller-Eberhard, Initiation of the alternative complement pathway due to spontaneous hydrolysis of the thioester of C3. Annals of the New York Academy of Sciences. ,vol. 421, pp. 291- 298 ,(1983) , 10.1111/J.1749-6632.1983.TB18116.X