Thrombotic thrombocytopenic purpura

作者: C Téllez-Hinojosa , Alberto Vazquez-Mellado , David Gómez-Almaguer , None

DOI: 10.1016/J.RMU.2015.10.001

关键词:

摘要: Thrombotic thrombocytopenic purpura (TTP) is a disease with high rate of mortality if proper treatment not instated. Plasmapheresis plasmatic exchange the choice. Diagnosis performed demonstrating microangiopathic hemolytic anemia, negative direct Coombs test and thrombocytopenia. Among clinical data, neurological renal alterations stand out. When there reasonable suspicion in diagnosis, plasmapheresis must be initiated immediately. There are different diseases that may similar to TTP signs symptoms, especially pregnant women. has risk relapse leave sequelae.

参考文章(45)
Miha Furlan, Rodolfo Robles, Max Solenthaler, Max Wassmer, Pierre Sandoz, Bernhard Lämmle, Deficient Activity of von Willebrand Factor–Cleaving Protease in Chronic Relapsing Thrombotic Thrombocytopenic Purpura Blood. ,vol. 89, pp. 3097- 3103 ,(1997) , 10.1182/BLOOD.V89.9.3097
C. John Sperati, Alison R. Moliterno, Thrombotic Microangiopathy Hematology/Oncology Clinics of North America. ,vol. 29, pp. 541- 559 ,(2015) , 10.1016/J.HOC.2015.02.002
Barbara Plaimauer, JA Kremer Hovinga, C Juno, MJ Wolfsegger, S Skalicky, M Schmidt, L Grillberger, M Hasslacher, P Knöbl, H Ehrlich, F Scheiflinger, None, Recombinant ADAMTS13 normalizes von Willebrand factor-cleaving activity in plasma of acquired TTP patients by overriding inhibitory antibodies. Journal of Thrombosis and Haemostasis. ,vol. 9, pp. 936- 944 ,(2011) , 10.1111/J.1538-7836.2011.04224.X
Malcolm R. Ogborn, Lorraine Hamiwka, Elaine Orrbine, David S. Newburg, Atul Sharma, Peter N. McLaine, Pamela Orr, Peter Rowe, Renal function in Inuit survivors of epidemic hemolytic-uremic syndrome Pediatric Nephrology. ,vol. 12, pp. 485- 488 ,(1998) , 10.1007/S004670050493
J-P. Westwood, H. Webster, S. McGuckin, V. McDonald, S. J. Machin, M. Scully, Rituximab for Thrombotic Thrombocytopenic Purpura: Benefit of Early Administration During Acute Episodes and Use of Prophylaxis to Prevent Relapse Journal of Thrombosis and Haemostasis. ,vol. 11, pp. 481- 490 ,(2013) , 10.1111/JTH.12114
Paul Coppo, Annette Bussel, Sabine Charrier, Christophe Adrie, Lionel Galicier, Emmanuelle Boulanger, Agnès Veyradier, Thierry Leblanc, Corinne Alberti, Elie Azoulay, Jean-Roger Le Gall, Benoît Schlemmer, High-dose plasma infusion versus plasma exchange as early treatment of Thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome Medicine. ,vol. 82, pp. 27- 38 ,(2003) , 10.1097/00005792-200301000-00003
Kenneth H Shumak, Gail A Rock, Rama C Nair, Canadian Apheresis Group., Late Relapses in Patients Successfully Treated for Thrombotic Thrombocytopenic Purpura Annals of Internal Medicine. ,vol. 122, pp. 569- 572 ,(1995) , 10.7326/0003-4819-122-8-199504150-00002
Myrna Pequeño-Luévano, Laura Villarreal-Martínez, José Carlos Jaime-Pérez, Andrés Gómez-de-León, Olga Graciela Cantú-Rodríguez, Oscar González-Llano, David Gómez-Almaguer, None, Low-dose rituximab for the treatment of acute thrombotic thrombocytopenic purpura: Report of four cases Hematology. ,vol. 18, pp. 233- 236 ,(2013) , 10.1179/1607845412Y.0000000073