Clinical features and management of type I gastric carcinoids

摘要: Type I gastric carcinoids (TIGCs) are related to chronic atrophic gastritis and characterized by hypergastrinemia hyperplasia of enterochromaffin-like cells. TIGCs the most frequently diagnosed all carcinoids, accounting for about 70–80 %. Endoscopically, present as small (<10 mm), polypoid lesions or, more frequently, smooth, rounded submucosal lesions. Histologically, arise in deep mucosa, with some invading submucosa. Most well-differentiated tumors, metastasis being rare. Therefore, patients generally have an excellent prognosis. Among currently available treatment options total gastrectomy, partial resection, antrectomy, endoscopic surveillance, although no consensus has been reached on their optimal management. Further studies needed develop better management TIGC.