作者: Mitsuhiro Takeda , JunGoo Jee , Akira Mei Ono , Tsutomu Terauchi , Masatsune Kainosho
DOI: 10.1021/JA907911Y
关键词: Chemistry 、 Analytical chemistry 、 Deuterium 、 Kinetic isotope effect 、 Inorganic chemistry 、 Tyrosine 、 Hydrogen exchange 、 Chemical shift
摘要: We describe a new NMR method for monitoring the individual hydrogen exchange rates of hydroxyl groups tyrosine (Tyr) residues in proteins. The utilizes (2S,3R)-[β2,e1,2-2H3;0,α,β,ζ-13...