Higher order oligomerization is required for H-NS family member MvaT to form gene-silencing nucleoprotein filament

作者: Ricksen S. Winardhi , Wenbo Fu , Sandra Castang , Yanan Li , Simon L. Dove

DOI: 10.1093/NAR/GKS669

关键词: DNANucleoproteinDNA-binding proteinNucleoidCell biologyGeneBiologyMutantTrans-ActivatorsMutationGenetics

摘要: … In summary, Figure 1 has shown that MvaT is able to simultaneously stiffen and fold the DNA, and that DNA folding is progressively enhanced as the concentration of MvaT increases. …

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