Epidemiology of deep sternal wound infection in cardiac surgery.

作者: Farzan Filsoufi , Javier G. Castillo , Parwis B. Rahmanian , Stafford R. Broumand , George Silvay

DOI: 10.1053/J.JVCA.2009.02.007

关键词: Myocardial infarctionSurgeryAnesthesiaAscending aortaComorbidityCardiac surgeryMortality rateMedicineOdds ratioAortic archRetrospective cohort study

摘要: Objectives The aim of this study was to investigate the incidence and predictors deep sternal wound infection (DSWI) in a contemporary cohort patients undergoing cardiac surgery. early late outcomes with complication also were analyzed. Design A retrospective consecutive surgery using computerized database based on New York State Department Health registry. Data collection performed prospectively. Setting university hospital (single institution). Participants Five thousand seven hundred ninety-eight who underwent between January 1998 December 2005 including isolated coronary artery bypass graft (CABG) (n = 2,749, 47%), single- or multiple-valve 1,280, 22%), combined valve CABG procedures 934, 16%), involving ascending aorta aortic arch 835, 15%). Interventions None. Measurements Main Results overall DSWI 1.8% 106). highest rate occurred after valve/CABG (2.4%, n 22) 19). Multivariate analysis revealed 11 DSWI: obesity (odds ratio [OR] 2.2), previous myocardial infarction (OR 2.1), diabetes 1.7), chronic obstructive pulmonary disease 2.3), preoperative length stay >3 days 1.9), calcification 2.7), 2.4), cardiopulmonary time 1.8), re-exploration for bleeding 6.3), respiratory failure 3.2). mortality 14.2% 15) versus 3.6% 205) control group (p Conclusion remains rare but devastating is associated significant comorbidity, increased mortality, reduced long-term survival.

参考文章(25)
P. S. Wong, E. Paul, A. Yohana, J. Wright, P. Magee, R. El Oakley, R. Walesby, Mediastinitis in patients undergoing cardiopulmonary bypass: risk analysis and midterm results. Journal of Cardiovascular Surgery. ,vol. 38, pp. 595- 600 ,(1997)
Alon Yellin, Yael Refaely, Michael Paley, David Simansky, Major bleeding complicating deep sternal infection after cardiac surgery. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 125, pp. 554- 558 ,(2003) , 10.1067/MTC.2003.31
M. C. Farinas, F. G. Peralta, J. M. Bernal, J. M. Rabasa, J. M. Revuelta, J. Gonzalez-Macias, Suppurative Mediastinitis After Open-Heart Surgery: A Case-Control Study Covering a Seven-Year Period in Santander, Spain Clinical Infectious Diseases. ,vol. 20, pp. 272- 279 ,(1995) , 10.1093/CLINIDS/20.2.272
Heyman Luckraz, Fiona Murphy, Steve Bryant, Susan C. Charman, Andrew J. Ritchie, Vacuum-assisted closure as a treatment modality for infections after cardiac surgery. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 125, pp. 301- 305 ,(2003) , 10.1067/MTC.2003.74
Traves D Crabtree, John E Codd, Victoria J Fraser, Marci S Bailey, Margaret A Olsen, Ralph J Damiano, Multivariate analysis of risk factors for deep and superficial sternal infection after coronary artery bypass grafting at a tertiary care medical center. Seminars in Thoracic and Cardiovascular Surgery. ,vol. 16, pp. 53- 61 ,(2004) , 10.1053/J.SEMTCVS.2004.01.009
Anne M. Eklund, Outi Lyytikäinen, Peter Klemets, Kaisa Huotari, Veli-Jukka Anttila, Kalervo A. Werkkala, Matti Valtonen, Mediastinitis After More Than 10,000 Cardiac Surgical Procedures The Annals of Thoracic Surgery. ,vol. 82, pp. 1784- 1789 ,(2006) , 10.1016/J.ATHORACSUR.2006.05.097
Carmelo A. Milano, Karen Kesler, Nancy Archibald, Daniel J. Sexton, Robert H. Jones, Mediastinitis After Coronary Artery Bypass Graft Surgery Risk Factors and Long-term Survival Circulation. ,vol. 92, pp. 2245- 2251 ,(1995) , 10.1161/01.CIR.92.8.2245
T Bruce Ferguson Jr, Bradley G Hammill, Eric D Peterson, Elizabeth R DeLong, Frederick L Grover, STS National Database Committee, A decade of change—risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990–1999: a report from the STS National Database Committee and the Duke Clinical Research Institute The Annals of Thoracic Surgery. ,vol. 73, pp. 480- 489 ,(2002) , 10.1016/S0003-4975(01)03339-2
Gianmaria Ottino, Ruggero De Paulis, Stefano Pansini, Giuseppe Rocca, Maria Vittoria Tallone, Chiara Comoglio, Paolo Costa, Fulvio Orzan, Mario Morea, Major Sternal Wound Infection after Open-Heart Surgery: A Multivariate Analysis of Risk Factors in 2,579 Consecutive Operative Procedures The Annals of Thoracic Surgery. ,vol. 44, pp. 173- 179 ,(1987) , 10.1016/S0003-4975(10)62035-8
J. F. Gummert, M. J. Barten, C. Hans, M. Kluge, N. Doll, T. Walther, B. Hentschel, D. V. Schmitt, F. W. Mohr, A. Diegeler, Mediastinitis and Cardiac Surgery - an Updated Risk Factor Analysis in 10,373 Consecutive Adult Patients The Thoracic and Cardiovascular Surgeon. ,vol. 50, pp. 87- 91 ,(2002) , 10.1055/S-2002-26691