Searches for exploitable biochemical differences between normal and cancer cells. VIII. Catabolism of purines and purine nucleotides by sonicates.

摘要: Radioactive purines and purine ribonucleotides were incubated with sonicates of mouse liver, intestine, Adenocarcinoma 755, Sarcoma 180, Leukemia L1210, rat Novikoff hepatoma, the residual substrates products catabolism isolated aid paper chromatography radioautography. Less occurred tumors than livers intestines, analysis data led to conclusion that decreased was primarily due xanthine oxidase activity.