Peripapillary Retinoschisis in Glaucoma: Association With Progression and OCT Signs of Müller Cell Involvement.

摘要: Purpose To examine demographic and clinical factors associated with glaucomatous peripapillary retinoschisis (PPRS) assess its association glaucoma progression. Methods Using a case control study design longitudinal data from cohort of 166 subjects diagnosis or suspect, we compared functional, structural, clinical, characteristics between PPRS cases controls. Results The frequency was 6.0% (12 eyes 10/166 subjects) two having in different sectors for total 15 events. There were no significant differences (P > 0.05) age, sex, visual acuity, central corneal thickness, intraocular pressure, presence vitreous adhesion However, tended to have higher cup-to-disc ratio = 0.06), thinner RNFL 0.02), worse field mean deviation (MD, P 0.06) than rate thinning faster (average: -2.8%/year; range: -7.4% 0.0%/year) controls (-1.3%/year; -4.4% 0.6%/year; 0.021). MD change (-0.49 dB/year; -2.0 0.9 dB/year) (-0.06 -0.8 0.3 0.030). OCT scans showed hyperreflective structures spanning the whose morphology spacing (50 ± 7 μm) are consistent Muller glia, causing signal attenuation casting "shadows" onto distal retina. Conclusions This is first report showing that overall deterioration specifically identify signs cell involvement.