Prospects for enhancement of targeted radionuclide therapy of cancer using ultrasound

作者: Richard J. Browning , Vineeth Rajkumar , R. Barbara Pedley , Robert J. Eckersley , Philip J. Blower

DOI: 10.1002/JLCR.3157

关键词: RadioimmunotherapyDrug deliveryChemistryCancerOncologyTargeted radionuclide therapyDistribution (pharmacology)UltrasoundTemperature sensitive liposomesPharmacologyInternal medicine

摘要: Ultrasound-mediated drug delivery is a promising means of enhancing delivery, distribution and effectiveness drugs within tumours. In this review, prospects for exploiting ultrasound to improve the tumour radiolabelled antibodies radioimmunotherapy overcome barriers imposed by microenvironment are discussed. Copyright © 2013 John Wiley & Sons, Ltd.

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