Hepatitis C Virus-Infected Patients Are ‘Spared’ from the Metabolic Syndrome but Not from Insulin Resistance. A Comparative Study of Nonalcoholic Fatty Liver Disease and Hepatitis C Virus-Related Steatosis

作者: Amedeo Lonardo , Stefano Ballestri , Luigi E Adinolfi , Enrico Violi , Lucia Carulli

DOI: 10.1155/2009/369703

关键词: ObesityInternal medicineNonalcoholic fatty liver diseaseInsulin resistanceMedicineGastroenterologySteatosisHepatitis CHepatitis C virusMetabolic syndromeFatty liver

摘要: BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis C feature steatosis insulin resistance (IR), conditions associated with the metabolic syndrome (MS).

参考文章(32)
Ching-Sheng Hsu, Chun-Jen Liu, Chen-Hua Liu, Chia-Chi Wang, Chi-Ling Chen, Ming-Yang Lai, Pei-Jer Chen, Jia-Horng Kao, Ding-Shinn Chen, High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C. Liver International. ,vol. 28, pp. 271- 277 ,(2007) , 10.1111/J.1478-3231.2007.01626.X
E. Tsochatzis, G.V. Papatheodoridis, E.K. Manesis, G. Kafiri, A.J. Archimandritis, [767] METABOLIC SYNDROME IS ASSOCIATED WITH SEVERE FIBROSIS IN CHRONIC VIRAL HEPATITIS AND NON-ALCOHOLIC STEATOHEPATITIS Journal of Hepatology. ,vol. 46, pp. S288- 89 ,(2007) , 10.1016/S0168-8278(07)62365-4
V. RATZIU, A. HEURTIER, L. BONYHAY, T. POYNARD, P. GIRAL, Review article: an unexpected virus–host interaction – the hepatitis C virus‐diabetes link Alimentary Pharmacology & Therapeutics. ,vol. 22, pp. 56- 60 ,(2005) , 10.1111/J.1365-2036.2005.02598.X
Amedeo Lonardo, Paola Loria, The hepatitis C virus‐associated dysmetabolic syndrome Hepatology. ,vol. 48, pp. 1018- 1019 ,(2008) , 10.1002/HEP.22425
Massimo Colombo, Giovanbattista Pinzello, Antonio Craxfì, Calogero Cammà, Savino Bruno, Vito Di Marco, Danilo Di Bona, Mariagrazia Rumi, Maria Vinci, Chiara Rebucci, Agostino Cividini, Giuseppe Pizzolanti, Ernesto Minola, Mario U. Mondelli, Insulin resistance is associated with steatosis in nondiabetic patients with genotype 1 chronic hepatitis C. Hepatology. ,vol. 43, pp. 64- 71 ,(2006) , 10.1002/HEP.20983
Amedeo Lonardo, Cesare Carani, Nicola Carulli, Paola Loria, ‘Endocrine NAFLD’ a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis Journal of Hepatology. ,vol. 44, pp. 1196- 1207 ,(2006) , 10.1016/J.JHEP.2006.03.005
Leon A. Adams, James F. Lymp, Jenny St. Sauver, Schuyler O. Sanderson, Keith D. Lindor, Ariel Feldstein, Paul Angulo, The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study Gastroenterology. ,vol. 129, pp. 113- 121 ,(2005) , 10.1053/J.GASTRO.2005.04.014
Peter J. Scheuer, Scoring of liver biopsies: are we doing it right? European Journal of Gastroenterology & Hepatology. ,vol. 8, pp. 1141- 1143 ,(1996) , 10.1097/00042737-199612000-00001
I. Friis‐Liby, F. Aldenborg, P. Jerlstad, K. Rundström, E. Björnsson, High prevalence of metabolic complications in patients with non‐alcoholic fatty liver disease Scandinavian Journal of Gastroenterology. ,vol. 39, pp. 864- 869 ,(2004) , 10.1080/00365520410006431