Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines.

作者: Chi-Hui Tang , Elizabeth A. Grimm

DOI: 10.1074/JBC.M310821200

关键词: Patient survivalATP synthaseApoptosisEndogenous nitric oxideCell biologyMelanoma cell lineBiologyCisplatinMelanomaDependent manner

摘要: The expression of inducible nitric-oxide synthase in melanoma tumor cells was recently shown to correlate strongly with poor patient survival after combination biochemotherapy (p

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