3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering

摘要: Injuries of bone and cartilage constitute important health issues costing the National Health Service billions pounds annually, in UK only. Moreover, these damages can become cause disability loss function for patients with associated social costs diminished quality life. The biomechanical properties two tissues are massively different from each other they not uniform within same tissue due to specific anatomic location function. In this perspective, engineering (TE) has emerged as a promising approach address complexities regeneration. Tissue aims at developing temporary three-dimensional multicomponent constructs promote natural healing process. Biomaterials, such hydrogels, currently extensively studied their ability reproduce both ideal 3D extracellular environment growth have adequate mechanical load bearing. This review will focus on use manufacturing techniques, namely electrospinning printing, that present promise fabrication complex composite gels applications.