Steady-state biofilm cultivation of Aspergillus niger D15 in a ceramic capillary membrane bioreactor
作者： Christian Endres , Sheena Janet Fraser , Wade Edwards , Sascha Beutel , Thomas Scheper
DOI: 10.4155/PBP.14.61
关键词: Pulp and paper industry 、 Microorganism 、 Xylanase 、 Steady state (chemistry) 、 Bioreactor 、 Biofilm 、 Aspergillus niger 、 Membrane bioreactor 、 Secondary metabolite 、 Biology 、 Biotechnology
摘要: Aim: Bioreactors are an essential component in every biotechnological process. Due to the multitude of different microbial and mammalian organisms used for production complex products, novel concepts customized cultivations necessary. Results: A ceramic capillary-based bioreactor enabling a approach steady-state biofilm cultivation is presented. model determination efficiency this system was developed by comparing its productivity conventional stirred tank reactors using recombinant xylanase Aspergillus niger D15 (xyn2) as Conclusion: The presented provides ideal platform shear-sensitive, filamentous growing microorganisms producing valuable secreted secondary metabolites or products.
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