An all-purpose tool for axon guidance.

作者: L. C. Schecterson , M. Bothwell

DOI: 10.1126/SCISIGNAL.147PE50

关键词: Signal transductionBiologyReceptorNeuroscienceAnatomyNeurotrophin Receptor p75Axon guidance

摘要: The functions of the 75-kilodalton neurotrophin receptor p75(NTR) have remained enigmatic despite nearly three decades study. Recent studies reveal that is a versatile co-receptor controls signaling by receptors for multiple ligands provide repellant guidance cues to developing axons.

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