作者: L. C. Schecterson , M. Bothwell
DOI: 10.1126/SCISIGNAL.147PE50
关键词: Signal transduction 、 Biology 、 Receptor 、 Neuroscience 、 Anatomy 、 Neurotrophin Receptor p75 、 Axon guidance
摘要: The functions of the 75-kilodalton neurotrophin receptor p75(NTR) have remained enigmatic despite nearly three decades study. Recent studies reveal that is a versatile co-receptor controls signaling by receptors for multiple ligands provide repellant guidance cues to developing axons.