Retinal astrocytes are immigrants from the optic nerve
作者： Takashi Watanabe , Martin C. Raff
DOI: 10.1038/332834A0
关键词: Nerve fibre layer 、 Retinal blood vessels 、 Optic nerve 、 Rat retina 、 Retinal 、 Phase contrast microscopy 、 Astrocyte 、 Retina 、 Pathology 、 Biology
摘要: The retina in most mammals contains two types of macroglial cells--Muller cells, which span the entire thickness retina, and astrocytes, are mainly confined to nerve fibre layer. Whereas Muller cells diffusely distributed all vertebrate retinae, presence distribution retinal astrocytes correlate with blood vessels: retinae that avascular contain no astrocytes; those vascularized a restricted region only region. This striking correlation between vascularization led Stone Dreher postulate immigrants enter its vasculature, although others have suggested they derive from cells. Here we provide strong evidence rat optic nerve.
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T E Ogden, Nerve fiber layer astrocytes of the primate retina: morphology, distribution, and density. Investigative Ophthalmology & Visual Science. ,vol. 17, pp. 499- 510 ,(1978)
Weber K, Shaw G, The intermediate filament complement of the retina: a comparison between different mammalian species. European Journal of Cell Biology. ,vol. 33, pp. 95- 104 ,(1984)
Santiago Ramón y Cajal, Mitchell Glickstein, The Structure of the Retina ,(1972)
MC Raff, ER Abney, J Cohen, R Lindsay, M Noble, Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics The Journal of Neuroscience. ,vol. 3, pp. 1289- 1300 ,(1983) , 10.1523/JNEUROSCI.03-06-01289.1983
G. S. Eisenbarth, F. S. Walsh, M. Nirenberg, Monoclonal antibody to a plasma membrane antigen of neurons Proceedings of the National Academy of Sciences of the United States of America. ,vol. 76, pp. 4913- 4917 ,(1979) , 10.1073/PNAS.76.10.4913
O. Marchesani, Die Morphologie der Glia im Nervus opticus und in der Retina, dargestellt nach den neuesten Untersuchungsmethoden und Untersuchungsergebnissen I. Mitteilung Albrecht von Græfes Archiv für Ophthalmologie. ,vol. 117, pp. 575- 605 ,(1926) , 10.1007/BF01863969
Richard G. Dixon, Lawrence F. Eng, Glial fibrillary acidic protein in the retina of the developing albino rat: An immunoperoxidase study of paraffin-embedded tissue The Journal of Comparative Neurology. ,vol. 195, pp. 305- 321 ,(1981) , 10.1002/CNE.901950210
Martin C. Raff, Robert H. Miller, Mark Noble, A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium Nature. ,vol. 303, pp. 390- 396 ,(1983) , 10.1038/303390A0
N. Ashton, Pathological Basis of Retrolental Fibroplasia British Journal of Ophthalmology. ,vol. 38, pp. 385- 396 ,(1954) , 10.1136/BJO.38.7.385
R. K. Small, P. Riddle, M. Noble, Evidence for migration of oligodendrocyte--type-2 astrocyte progenitor cells into the developing rat optic nerve. Nature. ,vol. 328, pp. 155- 157 ,(1987) , 10.1038/328155A0