Temporal Changes in DNA and RNA Synthesis in the Regenerating Liver of Hydrocortisone-treated Rats

摘要: The initial rise in DNA synthesis the regenerating liver of young adult rats is reversibly inhibited by administration hydrocortisone, 50 mg/kg, at beginning S phase, i.e. , 19 hr after partial hepatectomy. reinitiated approximately 31 postoperatively hydrocortisone-treated rat, with peak then occurring 36 hepatectomy, compared to 26 controls. Despite inhibition synthesis, rate ribosome formation increased 150 200% rats; similarly, following release elevated 120 over An analysis rates and processing rRNA nucleus accumulation products cytoplasm suggests that most increase due transport ribosomal subunits cytoplasm.