Targeting cancer with small-molecular-weight kinase inhibitors.
作者： Doriano Fabbro , Sandra W. Cowan-Jacob , Henrik Möbitz , Georg Martiny-Baron
DOI: 10.1007/978-1-61779-337-0_1
关键词: Intracellular 、 Cell 、 Enzyme 、 Cancer research 、 Drug discovery 、 Signal transduction 、 Cell growth 、 Biology 、 Receptor Protein-Tyrosine Kinases 、 Kinase
摘要: … a particular allosteric site of the mTOR kinase that results in … kinase drugs bind to the hinge region of the target kinase and … registered kinase drugs also have many other kinase targets …
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