Perioperative intraperitoneal chemotherapy for peritoneal surface malignancy

作者: Tristan D Yan , Oswald A Stuart , Dal Yoo , Paul H Sugarbaker

DOI: 10.1186/1479-5876-4-17

关键词: SurgeryIntraperitoneal chemotherapyAbdominal distensionDiseasePerioperativePseudomyxoma peritoneiPeritoneal Surface MalignancyMedicineAbdominopelvic cavityCancer

摘要: The treatment of peritoneal surface malignancy mainly focuses on diffuse malignant mesothelioma, pseudomyxoma peritonei from appendiceal cancer, and dissemination gastrointestinal ovarian cancers. Cancer progression causes implants to be distributed throughout the abdominopelvic cavity. These nodules plus ascitic fluid result in abdominal distension. As disease progresses, these tumors cause intestinal obstruction leading debilitating symptoms a greatly impaired quality life. In past, prognosis patients with was regarded dismal cure not an option. Recently, cytoreductive surgery combined perioperative intraperitoneal chemotherapy has shown improved survival selected this disease. To date, multiple different regimens have been used. This review currently use conjunction for at Washington Institute.

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