The development of supportive-care agents for patients with cancer.
作者： Theresa K. Neumann , MaryAnn Foote
DOI: 10.1016/S1387-2656(03)09011-2
关键词: Drug development 、 Marketing authorization 、 Medicine 、 Pharmacology 、 Population 、 Intensive care medicine 、 Cancer
摘要: Abstract As the population ages, a dramatic increase in number of cases cancer is expected and need for supportive-care agents, those used to ameliorate some side effects or its treatment, becomes more urgent. At present, products are available new agents being developed with novel mechanisms action modifications existing that improve performance. Because urgent such products, efficient development required deliver useful patients as rapidly possible. This chapter uses actual examples illustrate stages drug development, phase 1 through 3.
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