Health conditions associated with aging and end of life of adults with Down syndrome
作者： Anna J. Esbensen
DOI: 10.1016/S0074-7750(10)39004-5
关键词: Gerontology 、 Population 、 Lower risk 、 Obesity 、 Down syndrome 、 Life expectancy 、 Population ageing 、 Sleep apnea 、 Pediatrics 、 Medicine 、 Life course approach
摘要: Expectations for the life course of individuals with Down syndrome (DS) have changed, expectancy estimates increasing from 12 in 1949 to nearly 60 years age today (Bittles & Glasson, 2004; Penrose, 1949). Along this longer comes a larger population adults DS who display premature age-related changes their health. There is thus need provide specialized health care aging are at high risk some conditions and lower others. This review focuses on rates contributing factors medical that common or show age. The includes increased skin hair changes, early onset menopause, visual hearing impairments, adult seizure disorder, thyroid dysfunction, diabetes, obesity, sleep apnea musculoskeletal problems. different pattern associated mortality also reviewed.
elsevier.com
sci-hub.se 参考文章(114)
R. De La Torre, A. Casado, E. López-Fernández, D. Carrascosa, V. Ramírez, J. Sáez, Overexpression of copper-zinc superoxide dismutase in trisomy 21 Experientia. ,vol. 52, pp. 871- 873 ,(1996) , 10.1007/BF01938872
J. G. DEATON, THE MORTALITY RATE AND CAUSES OF DEATH AMONG INSTITUTIONALISED MONGOLS IN TEXAS Journal of Intellectual Disability Research. ,vol. 17, pp. 117- 122 ,(2008) , 10.1111/J.1365-2788.1973.TB01192.X
Klaus-Peter Dieckmann, Christian Rube, Rudiger-Peter Henke, Association of Down's Syndrome and Testicular Cancer The Journal of Urology. ,vol. 157, pp. 1701- 1704 ,(1997) , 10.1016/S0022-5347(01)64838-9
Zlatko ŠAre, R. H. A. Ruvalcaba, Vincent C. Kelley, Prevalence of thyroid disorder in Down syndrome. Clinical Genetics. ,vol. 14, pp. 154- 158 ,(2008) , 10.1111/J.1399-0004.1978.TB02121.X
Nicole Schupf, Deborah Pang, Bindu N. Patel, Wayne Silverman, Romaine Schubert, Florence Lai, Jennie K. Kline, Yaakov Stern, Michel Ferin, Benjamin Tycko, Richard Mayeux, Onset of dementia is associated with age at menopause in women with Down's syndrome Annals of Neurology. ,vol. 54, pp. 433- 438 ,(2003) , 10.1002/ANA.10677
M. P. Cosgrave, J. Tyrrell, M. McCarron, M. Gill, B. A. Lawlor, Age at onset of dementia and age of menopause in women with Down's syndrome. Journal of Intellectual Disability Research. ,vol. 43, pp. 461- 465 ,(1999) , 10.1046/J.1365-2788.1999.00192.X
F. Tyrer, L. K. Smith, C. W. McGrother, Mortality in adults with moderate to profound intellectual disability: a population-based study Journal of Intellectual Disability Research. ,vol. 51, pp. 520- 527 ,(2007) , 10.1111/J.1365-2788.2006.00918.X
Deborah Kapell, Beryle Nightingale, Ana Rodriguez, Joseph H. Lee, Warren B. Zigman, Nicole Schupf, Prevalence of Chronic Medical Conditions in Adults With Mental Retardation: Comparison With the General Population Mental Retardation. ,vol. 36, pp. 269- 279 ,(1998) , 10.1352/0047-6765(1998)036<0269:POCMCI>2.0.CO;2
Onofrio Resta, Maria Foschino Barbaro, Tiziana Giliberti, Gennaro Caratozzolo, Maria Cagnazzo, Franco Scarpelli, Maria Nocerino, Sleep related breathing disorders in adults with Down syndrome. Down Syndrome Research and Practice. ,vol. 8, pp. 115- 120 ,(2003) , 10.3104/REPORTS.138
Ira T. Lott, Florence Lai, Dementia in Down's syndrome: Observations from a neurology clinic Applied Research in Mental Retardation. ,vol. 3, pp. 233- 239 ,(1982) , 10.1016/0270-3092(82)90017-0