Use of common path phase sensitive spectral domain optical coherence tomography for refractive index measurements

作者: Yogesh Verma , Purnananda Nandi , K. Divakar Rao , Mrinalini Sharma , Pradeep Kumar Gupta

DOI: 10.1364/AO.50.0000E7

关键词: Refractive indexScatteringOptoelectronicsPhase retrievalMaterials sciencePhase sensitiveCommon pathOptical coherence tomographyOpticsFast Fourier transformOptical path length

摘要: We report the use of a common path phase sensitive spectral domain optical coherence tomography setup for measurement refractive index (RI) biomimetic material (glucose solution in water having intralipid as scattering medium) and single biological cell (keratinocyte). The RI glucose solutions could be measured with precision ∼0.00015, which corresponds to ∼2 nm length our setup. obtained keratinocyte was ∼0.0004.

参考文章(21)
Adolf Friedrich Fercher, Optical coherence tomography - development, principles, applications. Zeitschrift Fur Medizinische Physik. ,vol. 20, pp. 251- 276 ,(2010) , 10.1016/J.ZEMEDI.2009.11.002
Michael A. Choma, Audrey K. Ellerbee, Changhuei Yang, Tony L. Creazzo, Joseph A. Izatt, Spectral Domain Phase Microscopy Optics Letters. ,vol. 30, pp. 1162- 1164 ,(2005) , 10.1364/OL.30.001162
Sanjit K. Debnath, Mahendra P. Kothiyal, Seung-Woo Kim, Evaluation of spectral phase in spectrally resolved white-light interferometry: Comparative study of single-frame techniques Optics and Lasers in Engineering. ,vol. 47, pp. 1125- 1130 ,(2009) , 10.1016/J.OPTLASENG.2009.06.014
Rinat O. Esenaliev, Krill V. Larin, Irina V. Larina, Massoud Motamedi, Noninvasive monitoring of glucose concentration with optical coherence tomography Optics Letters. ,vol. 26, pp. 992- 994 ,(2001) , 10.1364/OL.26.000992
R. Leitgeb, C. Hitzenberger, Adolf Fercher, Performance of fourier domain vs. time domain optical coherence tomography. Optics Express. ,vol. 11, pp. 889- 894 ,(2003) , 10.1364/OE.11.000889
Frank Dubois, Luc Joannes, Jean-Claude Legros, Improved three-dimensional imaging with a digital holography microscope with a source of partial spatial coherence. Applied Optics. ,vol. 38, pp. 7085- 7094 ,(1999) , 10.1364/AO.38.007085
Adam M. Zysk, Steven G. Adie, Julian J. Armstrong, Matthew S. Leigh, Alexandre Paduch, David D. Sampson, Freddy T. Nguyen, Stephen A. Boppart, Needle-based refractive index measurement using low-coherence interferometry Optics Letters. ,vol. 32, pp. 385- 387 ,(2007) , 10.1364/OL.32.000385
Benjamin Rappaz, Pierre Marquet, Etienne Cuche, Yves Emery, Christian Depeursinge, Pierre J. Magistretti, Measurement of the integral refractive index and dynamic cell morphometry of living cells with digital holographic microscopy Optics Express. ,vol. 13, pp. 9361- 9373 ,(2005) , 10.1364/OPEX.13.009361
Y. Verma, K.D. Rao, M.K. Suresh, H.S. Patel, P.K. Gupta, Measurement of gradient refractive index profile of crystalline lens of fisheye in vivo using optical coherence tomography Applied Physics B. ,vol. 87, pp. 607- 610 ,(2007) , 10.1007/S00340-007-2689-4
James G Fujimoto, Optical coherence tomography for ultrahigh resolution in vivo imaging Nature Biotechnology. ,vol. 21, pp. 1361- 1367 ,(2003) , 10.1038/NBT892