Hirnstrukturelle Konsequenzen perinataler Stress- und Deprivationserfahrungen

作者: A.K. Braun , J. Bock

DOI: 10.1007/S00112-008-1783-Y

关键词: MedicineGynecologyBrain development

摘要: Der Artikel fasst die Bedeutung fruhkindlicher Erfahrungen fur funktionelle Reifung des Gehirns und Entwicklung geistiger psychischer Fahigkeiten aus neurobiologischer Sicht zusammen. Es wird dargelegt, dass vor allem emotionale einen synaptischen Selektions- Reorganisationsprozess in den prafrontalen kortikalen subkortikalen Regionen limbischen Systems auslosen somit Optimierung dieses „Belohnungssystems“ masgeblich steuern, welches bei Lern- Gedachtnisprozessen eine essenzielle Rolle spielt.

参考文章(33)
Dong Liu, Josie Diorio, Jamie C. Day, Darlene D. Francis, Michael J. Meaney, Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nature Neuroscience. ,vol. 3, pp. 799- 806 ,(2000) , 10.1038/77702
Ian C. G. Weaver, Rebecca J. Grant, Michael J. Meaney, Maternal behavior regulates long‐term hippocampal expression of BAX and apoptosis in the offspring Journal of Neurochemistry. ,vol. 82, pp. 998- 1002 ,(2002) , 10.1046/J.1471-4159.2002.01054.X
THOMAS G O'CONNOR, Michael Rutter, English and Romanian Adoptees Study Team, Attachment Disorder Behavior Following Early Severe Deprivation: Extension and Longitudinal Follow-up Journal of the American Academy of Child and Adolescent Psychiatry. ,vol. 39, pp. 703- 712 ,(2000) , 10.1097/00004583-200006000-00008
Robert G. Struble, Austin H. Riesen, Changes in cortical dendritic branching subsequent to partial social isolation in stumptailed monkeys. Developmental Psychobiology. ,vol. 11, pp. 479- 486 ,(1978) , 10.1002/DEV.420110511
Kazuo Okanoya, Naoko Tokimoto, Noriko Kumazawa, Sayaka Hihara, Atsushi Iriki, Tool-Use Training in a Species of Rodent: The Emergence of an Optimal Motor Strategy and Functional Understanding PLoS ONE. ,vol. 3, pp. e1860- ,(2008) , 10.1371/JOURNAL.PONE.0001860
Wladimir Ovtscharoff, Carina Helmeke, Katharina Braun, Lack of paternal care affects synaptic development in the anterior cingulate cortex Brain Research. ,vol. 1116, pp. 58- 63 ,(2006) , 10.1016/J.BRAINRES.2006.07.106
Brian H Harvey, Bruce S McEwen, Dan J Stein, Neurobiology of antidepressant withdrawal: implications for the longitudinal outcome of depression Biological Psychiatry. ,vol. 54, pp. 1105- 1117 ,(2003) , 10.1016/S0006-3223(03)00528-6
Katharina Braun, Petra Kremz, Wolfram Wetzel, Thomas Wagner, Gerd Poeggel, Influence of parental deprivation on the behavioral development in Octodon degus: modulation by maternal vocalizations. Developmental Psychobiology. ,vol. 42, pp. 237- 245 ,(2003) , 10.1002/DEV.10096