Pterygium and conjunctival ultraviolet autofluorescence in young Australian adults: the Raine study.

作者: Charlotte M McKnight , Justin C Sherwin , Seyhan Yazar , Hannah Forward , Alex X Tan

DOI: 10.1111/CEO.12455

关键词: AutofluorescenceMedicineBody mass indexInterquartile rangeOphthalmologyCohortSurgeryEyelidOdds ratioPopulationPterygium (conjunctiva)

摘要: Background Sun exposure is associated with several ophthalmic diseases, including pterygium which may develop in adolescence. This study reports the prevalence of and its associations a large cohort young Australian adults. Conjunctival ultraviolet autofluorescence, biomarker ocular sun exposure, has recently been characterized some populations. Design Cross-sectional population-based study. Participants One thousand three hundred forty-four subjects aged 18–22 years Western Pregnancy Cohort (Raine) Study. Methods Standardized colour autofluorescence photographs nasal temporal conjunctiva were taken, assessed for presence area autofluorescence. Sun protective factors by structured questionnaire. Main Outcome Measures Area conjunctival square millimetre (mm2) pterygium. Results Median total was 44.2 mm2 (interquartile range 20.2–69.8 mm2). Median higher than quadrants (23.8 mm2 vs. 18.9 mm2, P < 0.001), but did not differ according to age or gender. Higher body mass index lower levels Total increased increasing time spent outdoors. Prevalence 1.2% (95% confidence interval 0.6–1.8%), male gender (odds ratio 6.71, P = 0.012). Participants had significantly more those without (median 73.4 mm2 44.0 mm2, P = 0.001). Conclusions Conjunctival outdoors, pterygium. The association this other ophthalmohelioses, cataract, surface squamous neoplasia eyelid malignancy, yet be determined.

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