Diurnal variation of anterior scleral and conjunctival thickness

作者: Scott A. Read , David Alonso-Caneiro , Kelly A. Free , Elspeth Labuc-Spoors , Jaron K. Leigh

DOI: 10.1111/OPO.12288

关键词:

摘要: Purpose To examine whether anterior scleral and conjunctival thickness undergoes significant diurnal variation over a 24-hour period. Methods Nineteen healthy young adults (mean age 22 ± 2 years) with minimal refractive error spherical equivalent refraction -0.08 0.39 D), had measures of collected using segment optical coherence tomography (AS-OCT) at seven measurement sessions The the temporal sclera conjunctiva were determined 6 locations (each separated by 0.5 mm) varying distances from spur for each subject session. Results Both found to undergo variations in period (both p <0.01). exhibited similar pattern change, small magnitude thinning observed close midday, larger thickening early morning immediately after waking. amplitude change was 69 29 μm) compared (21 8 μm). its smallest location 56 17 whereas largest this (52 21 Conclusions This study provides first evidence occurring conjunctiva. Studies requiring precise these anatomical layers should therefore take time day into consideration. majority changes occurred waking sclera. Thickness other times smaller generally not statistically significant.

参考文章(40)
R. A. Sack, A. Tan, Kah Ooi Tan, Diurnal tear cycle: evidence for a nocturnal inflammatory constitutive tear fluid. Investigative Ophthalmology & Visual Science. ,vol. 33, pp. 626- 640 ,(1992)
Daniel F. Kripke, Robert N. Weinreb, Katharine M. Rex, Richard T. Loving, Rivak E. Hoffman, Michael D. Twa, John H. K. Liu, Neeru Gupta, Nocturnal elevation of intraocular pressure in young adults. Investigative Ophthalmology & Visual Science. ,vol. 39, pp. 2707- 2712 ,(1998)
Mertz Gw, Overnight swelling of the living human cornea. Journal of the American Optometric Association. ,vol. 51, pp. 211- ,(1980)
Andreas Ebneter, Nathanael U. Häner, Martin S. Zinkernagel, Metrics of the normal anterior sclera: imaging with optical coherence tomography Graefes Archive for Clinical and Experimental Ophthalmology. ,vol. 253, pp. 1575- 1580 ,(2015) , 10.1007/S00417-015-3072-5
David Alonso-Caneiro, Stephen J. Vincent, Michael J. Collins, Morphological changes in the conjunctiva, episclera and sclera following short-term miniscleral contact lens wear in rigid lens neophytes Contact Lens and Anterior Eye. ,vol. 39, pp. 53- 61 ,(2016) , 10.1016/J.CLAE.2015.06.008
Charlotte M McKnight, Justin C Sherwin, Seyhan Yazar, Hannah Forward, Alex X Tan, Alex W Hewitt, Elliot Smith, David Turton, Pippa Byrd, Craig E Pennell, Minas T Coroneo, David A Mackey, Pterygium and conjunctival ultraviolet autofluorescence in young Australian adults: the Raine study. Clinical and Experimental Ophthalmology. ,vol. 43, pp. 300- 307 ,(2015) , 10.1111/CEO.12455
Leo G. Carney, Nathan Efron, Oxygen levels beneath the closed eyelid. Investigative Ophthalmology & Visual Science. ,vol. 18, pp. 93- 95 ,(1979)
Deborah S. Laughton, Benjamin J. Coldrick, Amy L. Sheppard, Leon N. Davies, A program to analyse optical coherence tomography images of the ciliary muscle Contact Lens and Anterior Eye. ,vol. 38, pp. 402- 408 ,(2015) , 10.1016/J.CLAE.2015.05.007
Naoyuki Maeda, Optical Coherence Tomography for Corneal Diseases Eye & Contact Lens-science and Clinical Practice. ,vol. 36, pp. 254- 259 ,(2010) , 10.1097/ICL.0B013E3181EF0DBB
Xingru Zhang, Qingsong Li, Bing Liu, Huanming Zhou, Hanming Wang, Zhengyong Zhang, Minghong Xiang, Zhumei Han, Haidong Zou, In Vivo Cross-Sectional Observation and Thickness Measurement of Bulbar Conjunctiva Using Optical Coherence Tomography Investigative Opthalmology & Visual Science. ,vol. 52, pp. 7787- 7791 ,(2011) , 10.1167/IOVS.11-7749