作者: Scott A. Read , David Alonso-Caneiro , Kelly A. Free , Elspeth Labuc-Spoors , Jaron K. Leigh
DOI: 10.1111/OPO.12288
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摘要: Purpose To examine whether anterior scleral and conjunctival thickness undergoes significant diurnal variation over a 24-hour period. Methods Nineteen healthy young adults (mean age 22 ± 2 years) with minimal refractive error spherical equivalent refraction -0.08 0.39 D), had measures of collected using segment optical coherence tomography (AS-OCT) at seven measurement sessions The the temporal sclera conjunctiva were determined 6 locations (each separated by 0.5 mm) varying distances from spur for each subject session. Results Both found to undergo variations in period (both p <0.01). exhibited similar pattern change, small magnitude thinning observed close midday, larger thickening early morning immediately after waking. amplitude change was 69 29 μm) compared (21 8 μm). its smallest location 56 17 whereas largest this (52 21 Conclusions This study provides first evidence occurring conjunctiva. Studies requiring precise these anatomical layers should therefore take time day into consideration. majority changes occurred waking sclera. Thickness other times smaller generally not statistically significant.