The impact of manufacturing variables on in vitro release of clobetasol 17-propionate from pilot scale cream formulations.
作者： Ayeshah Fateemah Beebee Fauzee , Sandile Maswazi Khamanga , Roderick Bryan Walker
DOI: 10.3109/03639045.2013.842579
关键词: Response surface methodology 、 Innovator 、 Homogenization (chemistry) 、 Pilot scale 、 Food science 、 Clobetasol 、 Clobetasol 17-propionate 、 Central composite design 、 Mathematics
摘要: … Objectives: The purpose of the study was to evaluate the effect of different homogenization speeds and times, anchor speeds and cooling times on the viscosity and cumulative % …
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