Cold-activated brown adipose tissue in healthy men.
作者： Wouter D. van Marken Lichtenbelt , Joost W. Vanhommerig , Nanda M. Smulders , Jamie M.A.F.L. Drossaerts , Gerrit J. Kemerink
关键词: Capsinoids 、 Thermogenesis 、 Adipose tissue 、 Overweight 、 Thermogenin 、 PRDM16 、 Brown adipose tissue 、 Endocrinology 、 Medicine 、 Internal medicine 、 Body mass index
摘要: Background Studies in animals indicate that brown adipose tissue is important the regulation of body weight, and it possible individual variation adaptive thermogenesis can be attributed to variations amount or activity tissue. Until recently, presence was thought relevant only small mammals infants, with negligible physiologic relevance adult humans. We performed a systematic examination presence, distribution, lean obese men during exposure cold temperature. Brown-adipose-tissue studied relation composition energy metabolism. Methods 24 healthy — 10 who were (body-mass index [BMI] [the weight kilograms divided by square height meters], <25) 14 overweight (BMI, ≥25) under thermoneutral conditions (22°C) mild (16°C). Putative brown-adipose-tissue ...
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