Hepatitis B virus infection and the dialysis patient.

作者: Fabrizio Fabrizi , Piergiorgio Messa , Paul Martin

DOI: 10.1111/J.1525-139X.2008.00437.X

关键词: HBsAgHepatitis BDialysisInternal medicineViral loadKidney diseaseMedicineHepatitis B virusPopulationImmunologyLamivudine

摘要: Prevention of nosocomial transmission hepatitis B virus (HBV) has been a signal achievement in the management chronic kidney disease. The rate serum surface antigen (HBsAg) seropositivity patients on maintenance hemodialysis developed world is currently low (0-10%) but outbreaks acute HBV infection continue to occur this setting. prevalence within dialysis units developing countries appears higher (2-20%) based relatively few reports. Although data are limited, population diminishes survival; viral load HBsAg-positive reportedly and stable over time. Updated recommendations for HBsAg carriers have issued. No rigorously controlled treatment trials with either interferon or lamivudine therapy available.

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