Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain
作者： Keigo Komine , Hideki Shimodaira , Masashi Takao , Hiroshi Soeda , Xiaofei Zhang
DOI: 10.1002/HUMU.22794
关键词: Missense mutation 、 MUTYH 、 Protein-fragment complementation assay 、 Wild type 、 Adenomatous polyposis coli 、 Molecular biology 、 Genetics 、 Escherichia coli 、 Complementation 、 Biology 、 Mutagenesis (molecular biology technique)
摘要: … coli MutY and human MUTYH is shown; 47 mutations observed in MUTYH related to MAP are indicated. B: Suppression of spontaneous mutations by expression of wild-type MUTYH …
elsevier.com
sci-hub.se 参考文章(33)
Sucharita Kundu, Megan K. Brinkmeyer, Alison L. Livingston, Sheila S. David, Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer DNA Repair. ,vol. 8, pp. 1400- 1410 ,(2009) , 10.1016/J.DNAREP.2009.09.009
Masanobu Takahashi, Hideki Shimodaira, Corinne Andreutti-Zaugg, Richard Iggo, Richard D. Kolodner, Chikashi Ishioka, Functional Analysis of Human MLH1 Variants Using Yeast and In vitro Mismatch Repair Assays Cancer Research. ,vol. 67, pp. 4595- 4604 ,(2007) , 10.1158/0008-5472.CAN-06-3509
Amie K. Boal, Eylon Yavin, Jacqueline K. Barton, DNA repair glycosylases with a [4Fe-4S] cluster: a redox cofactor for DNA-mediated charge transport? Journal of Inorganic Biochemistry. ,vol. 101, pp. 1913- 1921 ,(2007) , 10.1016/J.JINORGBIO.2007.05.001
Simone Picelli, Pawel Zajac, Xiao-Lei Zhou, David Edler, Claes Lenander, Johan Dalén, Fredrik Hjern, Nils Lundqvist, Ulrik Lindforss, Lars Påhlman, Kennet Smedh, Anders Törnqvist, Jörn Holm, Martin Janson, Magnus Andersson, Susanne Ekelund, Louise Olsson, Joakim Lundeberg, Annika Lindblom, Common variants in human CRC genes as low-risk alleles. European Journal of Cancer. ,vol. 46, pp. 1041- 1048 ,(2010) , 10.1016/J.EJCA.2010.01.013
Olga A Lukianova, Sheila S David, A role for iron-sulfur clusters in DNA repair. Current Opinion in Chemical Biology. ,vol. 9, pp. 145- 151 ,(2005) , 10.1016/J.CBPA.2005.02.006
Vito G. D’Agostino, Anna Minoprio, Paola Torreri, Ilaria Marinoni, Cecilia Bossa, Tamara C. Petrucci, Alessandra M. Albertini, Guglielmina N. Ranzani, Margherita Bignami, Filomena Mazzei, Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis. DNA Repair. ,vol. 9, pp. 700- 707 ,(2010) , 10.1016/J.DNAREP.2010.03.008
M. Takao, Q.-M. Zhang, S. Yonei, A. Yasui, Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase Nucleic Acids Research. ,vol. 27, pp. 3638- 3644 ,(1999) , 10.1093/NAR/27.18.3638
David M. Noll, Arhonda Gogos, Joshua A. Granek, Neil D. Clarke, The C-terminal domain of the adenine-DNA glycosylase MutY confers specificity for 8-oxoguanine.adenine mispairs and may have evolved from MutT, an 8-oxo-dGTPase. Biochemistry. ,vol. 38, pp. 6374- 6379 ,(1999) , 10.1021/BI990335X
Sara Molatore, Maria Teresa Russo, Vito G. D'Agostino, Flavia Barone, Yoshihiro Matsumoto, Alessandra M. Albertini, Anna Minoprio, Paolo Degan, Filomena Mazzei, Margherita Bignami, Guglielmina Nadia Ranzani, MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay. Human Mutation. ,vol. 31, pp. 159- 166 ,(2010) , 10.1002/HUMU.21158
Stephanie Hicks, David A. Wheeler, Sharon E. Plon, Marek Kimmel, Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed. Human Mutation. ,vol. 32, pp. 661- 668 ,(2011) , 10.1002/HUMU.21490