Spatial and temporal dynamics of dengue fever in Peru: 1994-2006.

摘要: SUMMARYThe weekly number of dengue cases in Peru, South America, stratified by province for the period 1994-2006 were analysed conjunction with associated demographic, geographic and climatological data. Estimates reproduction number, moderately correlated population size (Spearman rho=0.28, P=0.03), had a median 1.76 (IQR 0.83-4.46). The distributions attack rates epidemic durations follow power-law (Pareto) (coefficient determination >85%, P<0.004). Spatial heterogeneity was highest coastal areas followed mountain jungle areas. Our findings suggest hierarchy transmission events during large 2000-2001 from to small when serotypes DEN-3 DEN-4 first identified rho=-0.43, P=0.03). need spatial temporal data high degree resolution not only increases our understanding dynamics but will also generate new hypotheses provide platform testing innovative control policies.