One-Pot Three-Component Mild Synthesis of 2-Aryl-3-(9-alkylcarbazol-3-yl)thiazolidin-4-ones
作者： Zheng Li , Anguo Zhu , Jingya Yang
DOI: 10.1002/JHET.1047
关键词: Chemistry 、 Aryl 、 Organic chemistry 、 Yield (chemistry) 、 Diethyl ether
摘要: A series of novel 2-aryl-3-(9-alkylcarbazol-3-yl)thiazolidin-4-ones were synthesized by one-pot three-component reactions 3-amino-9-alkylcarbazoles, aromatic aldehydes, and 2-mercaptoacetic acid using dicyclohexylcarbodiimide (DCC) as a cyclizing agent in dry diethyl ether at room temperature. This protocol has advantages mild condition, short reaction time, high yield, simple work-up procedure.
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