作者: John G. O'Grady
关键词: Gastroenterology 、 Combined Modality Therapy 、 Surgery 、 Liver transplantation 、 Medicine 、 Disease 、 Internal medicine 、 Primary sclerosing cholangitis 、 Treatment options 、 Drug resistance 、 Chemotherapy 、 Palliative care
摘要: 1. Resection rates for cholangiocarcinoma (unrelated to primary sclerosing cholangitis) have increased 54% 79%, and the subsequent 5-year survival are 24% 31%. 2. Multimodality approaches involving various combinations of chemotherapy, irradiation, surgery increasingly being used treat cholangiocarcinoma. 3. The role liver transplantation in management is limited by perception that it inappropriate use scarce organs when 25%. 4. Liver an important intervention patients with tumors remain unresectable after chemotherapy. extrahepatic disease responds chemotherapy controversial. Careful timing required avoid secondary drug resistance. 5. has been successfully applied a range rare hepatic malignancies, but small numbers preclude strong recommendations on appropriateness this practice.