Emerging roles for enteric glia in gastrointestinal disorders
作者： Keith A. Sharkey
DOI: 10.1172/JCI76303
关键词: Intestinal mucosa 、 Enteric nervous system 、 Motility 、 Inflammation 、 Immune system 、 Immunology 、 Neuroglia 、 Enteroendocrine cell 、 Biology 、 Epithelial barrier function
摘要: Enteric glia are important components of the enteric nervous system (ENS) and also form an extensive network in mucosa gastrointestinal (GI) tract. Initially regarded as passive support cells, it is now clear that they actively involved cellular integrators control motility epithelial barrier function. a molecular bridge between nerves, enteroendocrine immune depending on their location. This Review highlights role GI disorders defense functions gut, notably states inflammation. It discusses involvement neurological diseases involve
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