Covalently Crosslinked and Physically Stable Polymer Coatings with Chemically Labile and Dynamic Surface Features Fabricated by Treatment of Azlactone-Containing Multilayers with Alcohol-, Thiol-, and Hydrazine-Based Nucleophiles

摘要: We report approaches to the design of covalently crosslinked and physically stable surface coatings with chemically labile dynamic features based on functionalization azlactone-containing materials alcohol-, thiol-, hydrazine-based nucleophiles. Past studies demonstrate that residual azlactone groups in polymer multilayers fabricated by reactive layer-by-layer assembly poly(2-vinyl-4,4-dimethylazlactone) branched poly(ethylenimine) can react amine-based nucleophiles impart new bulk properties through creation amide/amide-type bonds. Here, we these also be functionalized using less nucleophilic alcohol- or thiol-containing compounds, an organic catalyst, converted acylhydrazine direct treatment hydrazine. These methods (i) broaden pool molecules used for post-fabrication i...