In situ Delivery of Antigen to DC-SIGN + CD14 + Dermal Dendritic Cells Results in Enhanced CD8 + T-Cell Responses

作者: Cynthia M. Fehres , Astrid J. van Beelen , Sven C.M. Bruijns , Martino Ambrosini , Hakan Kalay

DOI: 10.1038/JID.2015.152

关键词: CD14BiologyImmunologyCell biologyAntigenMajor histocompatibility complexDendritic cellDC-SIGNCytotoxic T cellToll-like receptorCD8

摘要: … T cells. Here we show using a human skin explant model that the in situ targeting of antigens to DC-SIGN using glycan-modified liposomes enhances the antigen-presenting capacity of …

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