Inventing probiotic functional foods for patients with allergic disease.

摘要: Objective The primary objective of this review is to discuss the rationale for and applicability probiotics as part nutritional approach prevention management allergic disease. Data Sources This represents a synthesis recent literature published in fields probiotics, nutrition, Study Selection expert opinions authors were used select relevant data review. Results hygiene hypothesis suggests that disease may arise from lack counterbalancing microbial exposure at an early age. Thus, initial compositional development gut microbiota considered key determinant both immune responder phenotype normal barrier functions. A wide range documents specific actions selected probiotics. regulatory role has been demonstrated improving clinical course or preventing atopic eczema infants given probiotic-supplemented diet. In addition, certain types fatty acids antioxidants have proposed protective effects against allergy diminish inflammatory response Conclusions increase prevalence during past decades likely be explained by changes environment, including reduced altered food consumption. Scientifically composed functional foods containing other components offer strategy Further research needed characterize clarify mechanisms action control physiologic processes not only evolution at-risk populations but also diseases.