Capillary loss precedes the cognitive impairment induced by fractionated whole-brain irradiation: A potential rat model of vascular dementia

作者: William R. Brown , Robert M. Blair , Dixon M. Moody , Clara R. Thore , Stephanie Ahmed

DOI: 10.1016/J.JNS.2007.01.014

关键词: Dose fractionationCognitive disorderPathologyVascular dementiaRadial arm mazeCentral nervous system diseaseStereologyPsychologyDementiaBrain ischemia

摘要: … , this rat model shows cognitive impairment and a chronic and progressive decrease in vascular … will be required to determine if this rat model is a valid model of vascular dementia. …

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