Evidence for diploidy and mating in trypanosomes

作者: A. Tait

DOI: 10.1038/287536A0

关键词: MultinucleatePloidySexual reproductionGeneticsTrypanosoma bruceiPopulationBiologyIsozyme

摘要: The question of whether any sexual process takes place at some stage the life cycle trypanosome has often been raised and crosses between different drug-resistant strains have provided no convincing answer. Multinucleate forms trypanosomes observed by electron microscopy but their significance origin remain obscure. As part a study aimed examining speciation genetics Trypanosoma brucei complex trypanosomes, series isolates from population T.b. screened for electrophoretic variation in 19 enzymes. results this survey, reported here, provide strong evidence that are diploid undergo random mating recombination.

参考文章(12)
P.J. Walker, Reproduction and Heredity in Trypanosomes A Critical Review Dealing Mainly with the African Species in the Mammalian Host International Review of Cytology-a Survey of Cell Biology. ,vol. 17, pp. 51- 98 ,(1964) , 10.1016/S0074-7696(08)60405-2
Harry. Harris, D. A. Hopkinson, Handbook of enzyme electrophoresis in human genetics ,(1976)
VERONICA KILGOUR, D. G. GODFREY, Species-characteristic Isoenzymes of Two Aminotransferases in Trypanosomes Nature. ,vol. 244, pp. 69- 70 ,(1973) , 10.1038/NEWBIO244069A0
L.G. Goodwin, Eighteenth seminar on trypanosomiasis Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 72, pp. 109- 122 ,(1978) , 10.1016/0035-9203(78)90046-9
W.E Ormerod, S Venkatesan, An amastigote phase of the sleeping sickness trypanosome Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 65, pp. 736- 741 ,(1971) , 10.1016/0035-9203(71)90088-5
Sheila M. Lanham, D.G. Godfrey, Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose Experimental Parasitology. ,vol. 28, pp. 521- 534 ,(1970) , 10.1016/0014-4894(70)90120-7
MICHAEL A. MILES, ADELSON SOUZA, MARINETE POVOA, JEFFREY J. SHAW, RALPH LAINSON, PETER J. TOYE, Isozymic heterogeneity of Trypanosoma cruzi in the first autochthonous patients with Chagas' disease in Amazonian Brazil. Nature. ,vol. 272, pp. 819- 821 ,(1978) , 10.1038/272819A0
D.G. Godfrey, Veronica Kilgour, Enzyme electrophoresis in characterizing the causative organism of Gambian trypanosomiasis Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 70, pp. 219- 224 ,(1976) , 10.1016/0035-9203(76)90043-2