作者: Gerald D. Buckberg , H. Cecil Coghlan , Francisco Torrent-Guasp
关键词: Cardiology 、 Hemodynamics 、 Magnetic resonance imaging 、 Anatomy 、 Internal medicine 、 Dilated cardiomyopathy 、 Structure and function 、 Heart failure 、 Medicine 、 Cardiovascular physiology 、 Isovolumetric contraction 、 Electrophysiology
摘要: A macroscopic structure of an elliptic heart, formed by the helix provided apical loop, is defined and related, initially, to normal function. To define sequence progressive muscular activity, cardiac pressure, magnetic resonance imaging (MRI), multiple gated acquisition (MUGA) records are reviewed. This novel format for helical heart then compared with historic studies ventricular structure. New concepts will show how basal loops cause initial isovolumetric contraction, together factors responsible contractile lengthening filling suction. The interaction these muscular-functional changes correlated basic electrophysiology (excitation-contraction) set stage alterations produced changing apex a sphere during congestive failure. Macroscopic in failure, which convert ellipse globe, as underpinning dilated cardiomyopathy. It our hypothesis that commonality this spheric left substrate becomes ischemic, idiopathic,