YAP inhibits squamous transdifferentiation of Lkb1-deficient lung adenocarcinoma through ZEB2-dependent DNp63 repression
作者： Yijun Gao , Wenjing Zhang , Xiangkun Han , Fuming Li , Xujun Wang
DOI: 10.1038/NCOMMS5629
关键词: Cancer research 、 Carcinogenesis 、 Transdifferentiation 、 Squamous Differentiation 、 Reprogramming 、 Psychological repression 、 Immunology 、 Biology 、 Hippo signaling pathway 、 Adenocarcinoma 、 Effector
摘要: … adenocarcinoma through ZEB2-dependent DNp63 repression | Nature Communications … Thank you for visiting nature.com. You are using a browser version with limited support for CSS. …
nature.com
harvard.edu
irgrid.ac.cn参考文章(49)
Toshihiro Shiozawa, Genichiro Ishii, Koichi Goto, Kanji Nagai, Sachiyo Mimaki, Shotaro Ono, Seiji Niho, Satoshi Fujii, Yuichiro Ohe, Katsuya Tsuchihara, Atsushi Ochiai, Clinicopathological characteristics of EGFR mutated adenosquamous carcinoma of the lung Pathology International. ,vol. 63, pp. 77- 84 ,(2013) , 10.1111/PIN.12033
Dawang Zhou, Claudius Conrad, Fan Xia, Ji-Sun Park, Bernhard Payer, Yi Yin, Gregory Y. Lauwers, Wolfgang Thasler, Jeannie T. Lee, Joseph Avruch, Nabeel Bardeesy, Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene Cancer Cell. ,vol. 16, pp. 425- 438 ,(2009) , 10.1016/J.CCR.2009.09.026
Isabel Serrano, Paul C. McDonald, Frances Lock, William J. Muller, Shoukat Dedhar, Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase Nature Communications. ,vol. 4, pp. 2976- 2976 ,(2013) , 10.1038/NCOMMS3976
Yang Wang, Qianze Dong, Qingfu Zhang, Zixuan Li, Enhua Wang, Xueshan Qiu, None, Overexpression of yes‐associated protein contributes to progression and poor prognosis of non‐small‐cell lung cancer Cancer Science. ,vol. 101, pp. 1279- 1285 ,(2010) , 10.1111/J.1349-7006.2010.01511.X
Chuen Yan Leung, Magdalena Zernicka-Goetz, Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms. Nature Communications. ,vol. 4, pp. 2251- 2251 ,(2013) , 10.1038/NCOMMS3251
L. V. Sequist, B. A. Waltman, D. Dias-Santagata, S. Digumarthy, A. B. Turke, P. Fidias, K. Bergethon, A. T. Shaw, S. Gettinger, A. K. Cosper, S. Akhavanfard, R. S. Heist, J. Temel, J. G. Christensen, J. C. Wain, T. J. Lynch, K. Vernovsky, E. J. Mark, M. Lanuti, A. J. Iafrate, M. Mino-Kenudson, J. A. Engelman, Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors Science Translational Medicine. ,vol. 3, ,(2011) , 10.1126/SCITRANSLMED.3002003
Bin Zhao, Qun-Ying Lei, Kun-Liang Guan, None, The Hippo–YAP pathway: new connections between regulation of organ size and cancer Current Opinion in Cell Biology. ,vol. 20, pp. 638- 646 ,(2008) , 10.1016/J.CEB.2008.10.001
Angela A. Steinhardt, Mariana F. Gayyed, Alison P. Klein, Jixin Dong, Anirban Maitra, Duojia Pan, Elizabeth A. Montgomery, Robert A. Anders, Expression of Yes-associated protein in common solid tumors Human Pathology. ,vol. 39, pp. 1582- 1589 ,(2008) , 10.1016/J.HUMPATH.2008.04.012
Cédric Blanpain, Tracing the cellular origin of cancer Nature Cell Biology. ,vol. 15, pp. 126- 134 ,(2013) , 10.1038/NCB2657
M Yuan, V Tomlinson, R Lara, D Holliday, C Chelala, T Harada, R Gangeswaran, C Manson-Bishop, P Smith, S A Danovi, O Pardo, T Crook, C A Mein, N R Lemoine, L J Jones, S Basu, Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death & Differentiation. ,vol. 15, pp. 1752- 1759 ,(2008) , 10.1038/CDD.2008.108