Recent Advances in the Detection of Neonatal Candidiasis.

作者: Laura Corbin Downey , P. Brian Smith , Daniel K. Benjamin , Michael Cohen-Wolkowiez

DOI: 10.1007/S12281-010-0002-1

关键词: Neonatal CandidiasisBlood cultureGenetic algorithmPediatricsTropical medicineMedicineIntensive care medicine

摘要: Neonatal candidiasis is serious and often fatal. Blood culture, the standard for diagnosis, has a sensitivity of 50% or less, isolate speciation susceptibility takes several days. This review explores recent advances in Candida detection using various diagnostic strategies.

参考文章(36)
Isabel Kurlat, Shirley M. Young, Carlos M. Botas, Augusto Sola, Disseminated Candidal Infections and Intravenous Hydrocortisone in Preterm Infants Pediatrics. ,vol. 95, pp. 883- 887 ,(1995)
M. Khlif, C. Mary, H. Sellami, A. Sellami, H. Dumon, A. Ayadi, S. Ranque, Evaluation of nested and real-time PCR assays in the diagnosis of candidaemia. Clinical Microbiology and Infection. ,vol. 15, pp. 656- 661 ,(2009) , 10.1111/J.1469-0691.2009.02762.X
S. Oliveri, L. Trovato, P. Betta, M.G. Romeo, G. Nicoletti, Experience with the Platelia Candida ELISA for the diagnosis of invasive candidosis in neonatal patients. Clinical Microbiology and Infection. ,vol. 14, pp. 391- 393 ,(2008) , 10.1111/J.1469-0691.2007.01938.X
J. Loeffler, H. Hebart, P. Cox, N. Flues, U. Schumacher, H. Einsele, Nucleic acid sequence-based amplification of Aspergillus RNA in blood samples. Journal of Clinical Microbiology. ,vol. 39, pp. 1626- 1629 ,(2001) , 10.1128/JCM.39.4.1626-1629.2001
Daniel K Benjamin Jr, Barbara J Stoll, Avory A Fanaroff, Scott A McDonald, William Oh, Rosemary D Higgins, Shahnaz Duara, Kenneth Poole, Abbot Laptook, Ronald Goldberg, National Institute of Child Health and Human Development Neonatal Research Network, None, Neonatal Candidiasis Among Extremely Low Birth Weight Infants: Risk Factors, Mortality Rates, and Neurodevelopmental Outcomes at 18 to 22 Months Pediatrics. ,vol. 117, pp. 84- 92 ,(2006) , 10.1542/PEDS.2004-2292
Angelina Pera, Angela Byun, Steven Gribar, Rama Schwartz, Deepak Kumar, Prabhu Parimi, Dexamethasone Therapy and Candida Sepsis in Neonates Less Than 1250 Grams Journal of Perinatology. ,vol. 22, pp. 204- 208 ,(2002) , 10.1038/SJ.JP.7210699
Lutz Eric Lehmann, Klaus-Peter Hunfeld, Thomas Emrich, Gerd Haberhausen, Heimo Wissing, Andreas Hoeft, Frank Stüber, A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples. Medical Microbiology and Immunology. ,vol. 197, pp. 313- 324 ,(2008) , 10.1007/S00430-007-0063-0
Kristina N. Feja, Fann Wu, Kevin Roberts, Maureen Loughrey, Mirjana Nesin, Elaine Larson, Phyllis Della-Latta, Janet Haas, Jeannie Cimiotti, Lisa Saiman, Risk Factors for Candidemia in Critically Ill Infants: A Matched Case-control Study The Journal of Pediatrics. ,vol. 147, pp. 156- 161 ,(2005) , 10.1016/J.JPEDS.2005.02.021
Lisa Saiman, Elizabeth Ludington, Michael Pfaller, Sigfrido Rangel-Frausto, TODD R WIBLIN, Jeffrey Dawson, Henry M Blumberg, Jan E Patterson, Michael Rinaldi, Jack E Edwards, Richard P Wenzel, William Jarvis, National Epidemiology of Mycosis Survey Study Group, Risk factors for candidemia in neonatal intensive care unit patients Pediatric Infectious Disease Journal. ,vol. 19, pp. 319- 324 ,(2000) , 10.1097/00006454-200004000-00011