Oral Extended-Release Formulations
作者： Anette Larsson , Susanna Abrahmsén-Alami , Anne Juppo
DOI: 10.1002/9780470571224.PSE369
关键词: Dosage form 、 Hydrophilic matrix 、 Pharmacology 、 Matrix (chemical analysis) 、 Drug 、 Chromatography 、 Drug release 、 Chemistry 、 Extended release 、 Extended Release Formulations
摘要: In order to achieve therapeutic effect, a drug needs reach the right place in body at time. For some drugs, this may be achieved by simple solutions or solid dosage forms with an instant release while, for others, one has modify release, such as modified-release (MR) formulations and oral extended-release (ER) formulations. This article focuses on formulation principles manufacturing of different ER formulations, insoluble matrix tablets, membrane-coated extended hydrophilic tablets. Keywords: modified-release formulations; oral formulations; insoluble tablets; membrane-coated release; hydrophilic tablets
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