Methods for improving sperm functionality

作者: Bridget Lee Dicker , Francesca De Gregorio , Jiwon Hong , Keith Hudson , Shakeela Nathalia Jayasinghe

DOI:

关键词: InseminationFertilityBiologyAndrologySpermFemale Reproductive TractArtificial inseminationMotility

摘要: Methods for improving the functionality and/or fertility of sperm, example, by enhancing motility and extending lifespan sperm in female reproductive tract, adding PEG to surface are provided. Such methods may be used artificial insemination reduce number needed improve conception rates.

参考文章(85)
Dettmar Frese, Birgit Sieg, Detlef Rath, Primoz Klinc, Method for preservation for gender specific selection of mammalian spermatozoa ,(2004)
U Kvist, H Rodríguez-Martínez, A Johannisson, J J Calvete, J M Vázquez, M Wallgren, L Sanz, F J Peña, F Saravia, E A Martínez, J Roca, The physiological roles of the boar ejaculate. Society of Reproduction and Fertility supplement. ,vol. 66, pp. 1- 21 ,(2009)
Juan J Calvete, Libia Sanz, Insights into structure-function correlations of ungulate seminal plasma proteins. Spermatology. Proceedings of the 10th International Symposium on Spermatology held at El Escorial, Madrid, Spain, 17-22 September 2006.. ,vol. 65, pp. 201- 215 ,(2007)
A Abuchowski, T van Es, N C Palczuk, F F Davis, Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. Journal of Biological Chemistry. ,vol. 252, pp. 3578- 3581 ,(1977) , 10.1016/S0021-9258(17)40291-2
Harkiss D, Bowie H, Buckingham D, Richardson Dw, West Km, Aitken Rj, Sperm penetration into a hyaluronic acid polymer as a means of monitoring functional competence. Journal of Andrology. ,vol. 13, pp. 44- 54 ,(1992) , 10.1002/J.1939-4640.1992.TB01626.X
Robin A.J. Smith, Kenneth Martin Taylor, Mitoquinone Derivatives Used as Mitochondrially Targeted Antioxidants ,(2004)
A Abuchowski, J R McCoy, N C Palczuk, T van Es, F F Davis, Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. Journal of Biological Chemistry. ,vol. 252, pp. 3582- 3586 ,(1977) , 10.1016/S0021-9258(17)40292-4
Stephen K. Hunter, James R. Scott, Dale Hull, Ronald L. Urry, The gamete and embryo compatibility of various synthetic polymers. Fertility and Sterility. ,vol. 50, pp. 110- 116 ,(1988) , 10.1016/S0015-0282(16)60017-1