Causes of death and cardiovascular complications in adolescents and adults with congenitally malformed hearts: an autopsy study of 102 cases

摘要: Objectives To identify the causes of death and main cardiovascular complications in adolescents adults with congenitally malformed hearts. Design Retrospective review 102 necropsy reports from a tertiary centre obtained over period 19 years. Methods The diagnosis, operated or non-operated state defect, cause death, were related to age gender. Other clinically relevant conditions, identifiable sequels previous diseases, also noted. Results ages ranged 15 69 years, mean 31.1 median 28 no difference detected according Of patients, two-thirds had been submitted at least one cardiac surgery. was significantly higher patients (p = 0.003). most prevalent whole group recent surgery, found one-third. From them, two-fifths corresponded reoperations. Among others, failure terminal another third, second pulmonary thromboembolism just one-fifth, presenting significant association histopathological signs hypertension 0.011). Infection 7.8% all previously operated. Acute infective endocarditis present indication for surgery one-tenth this cohort having 27.8 There statistically between occurrence defects causing low blood flow 0.043). Conclusions Data derived necropsies congenital heart can help multidisciplinary team refine both their diagnosis treatment.