Clinical course and complications of infective endocarditis in patients growing up with congenital heart disease

摘要: Background: Although a high number of patients with congenital heart disease (CHD) undergo surgical palliation or definite correction up to adolescence, adult (ACHD) may remain potential lifelong risk factor for infective endocarditis (IE) in growing (GUCH). Methods: In retrospective case study tertiary care center long-term clinical course and complications IE GUCH were analysed. Results: Data 52 CHD, who fulfilled the Saiman criteria treated between April 1986 March 2001, identified: Risk factors previous cardiovascular operation (51.9%), use foreign material (38.5%), dental other procedures without recommended antibiotic prophylaxis (25.0%), cardiac catheterization (5.8%). Staphylococcal (38.9%) streptococcal species (35.2%) cultivated most cases as causative microorganisms. Complications were: recurrence (7.7%), septic embolisms (30.8%) leading central nervous embolism pulmonary arteries renal (1.9%), extremities (9.6%), infarction spleen (1.9%). Other (23.1%) extracardiac (13.5%) frequent. The need re-operations during after was (67.3%). hospital mortality 1.9%, late 7.7%. Conclusions: Patients CHD show broad spectrum complications. They lead complicative short- death re-operation. Efforts have be made improve outcome ACHD by an interdisciplinary cooperation.